| Date | Location | Result | |
| 03/02/18 | Nashville, Tenn. (Allen Arena) | Lipscomb 95, USC Upstate 53 | Box score |
| 02/24/18 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 74, NJIT 67 | Box score |
| 02/19/18 | Jacksonville, Fla. (UNF Arena) | North Florida 79, USC Upstate 61 | Box score |
| 02/17/18 | Jacksonville, Fla. - Swisher Gym | Jacksonville 65, USC Upstate 49 | Box score |
| 02/12/18 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 69, Stetson 64 | Box score |
| 02/10/18 | Spartanburg, S.C. (G.B. Hodge Center) | FGCU 88, USC Upstate 44 | Box score |
| 02/07/18 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 80, Lipscomb 64 | Box score |
| 2/3/18 | Kennesaw, Ga. (KSU Convocation Center) | USC Upstate 70, Kennesaw State 64 | Box score |
| 02/01/18 | Allen Arena (Nashville, Tenn.) | Lipscomb 97, USC Upstate 78 | Box score |
| 01/27/18 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 65, Kennesaw State 61 | Box score |
| 01/22/18 | Spartanburg, S.C. (G.B. Hodge Center) | Jacksonville 71, USC Upstate 45 | Box score |
| 01/20/18 | Spartanburg, S.C. (G.B. Hodge Center) | North Florida 65, USC Upstate 61 | Box score |
| 01/15/18 | Fort Myers, Fla. | FGCU 93, USC Upstate 60 | Box score |
| 1/13/18 | DeLand, Fla. (Edmunds Center) | Stetson 62, USC Upstate 61 | Box score |
| 1/6/18 | Newark, NJ - Wellness and Events Center | USC Upstate 95, NJIT 57 | Box score |
| 01/02/18 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 109, Brevard 39 | Box score |
| 12/30/17 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 66, N.C. Central 61 | Box score |
| 12/19/17 | Stillwater, Okla. (Gallagher-Iba Arena) | Oklahoma State 108, USC Upstate 71 | Box score |
| 12/16/17 | Spartanburg, S.C. (G.B. Hodge Center) | UNC Asheville 76, USC Upstate 70 | Box score |
| 12/9/17 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 63, South Carolina St. 44 | Box score |
| 12/5/17 | Williamsburg, Va. (Kaplan Arena) | William & Mary 83, USC Upstate 63 | Box score |
| 12/3/17 | Spartanburg, S.C. (G.B. Hodge Center) | Furman 80, USC Upstate 59 | Box score |
| 11/30/17 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 79, Bob Jones 45 | Box score |
| 11/28/17 | Boiling Springs, NC (Paul Porter Arena) | Gardner-Webb 60, USC Upstate 39 | Box score |
| 11/24/17 | Spartanburg, S.C. (G.B. Hodge Center) | Omaha 69, USC Upstate 66 | Box score |
| 11/21/17 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 71, Converse 51 | Box score |
| 11/19/17 | Buies Creek, N.C. (Gore Arena) | Campbell 69, USC Upstate 49 | Box score |
| 11/17/17 | Cassell Coliseum, Blacksburg, Va. | Virginia Tech 87, USC Upstate 56 | Box score |
| 11/15/17 | Spartanburg, S.C. (G.B. Hodge Center) | Presbyterian College 83, USC Upstate 69 | Box score |
| 11/10/17 | Greenville, N.C. (Minges Coliseum) | ECU 66, USC Upstate 53 | Box score |